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3 out of 4 intubated people were discharged right after treatment2 from four individuals had been extubated inside 24 hrs of dosing LEXINGTON, Mass., Feb. 04, 2021 (GLOBE NEWSWIRE) -- Agenus Inc. (NASDAQ: AGEN), an immuno-oncology company with an extensive pipeline of checkpoint antibodies, mobile therapies, adjuvants, and vaccines designed to activate immune response to cancers and infections, now announced favourable preliminary outcomes from its Stage 1 demo of iNKT cell therapy in clients with reasonable to critical signs and symptoms of COVID-19 by means of its subsidiary, AgenTus Therapeutics. AgenTus is actively accruing and treating here sufferers with critical indications of COVID-19 with its proprietary allogeneic iNKT cell therapy, with dose escalation underway. Preliminary facts show that on the four sufferers dosed to date, three people (75%) were extubated and unveiled immediately after cure. Notably, two of such people (fifty%) were being extubated within 24 several hours of dosing. “We have been heartened by these early effects, which counsel that pretty Unwell individuals who had been admitted to intensive care models and intubated may perhaps take pleasure in a single administration of our iNKT mobile therapy,†claimed Dr. Garo Armen, Chairman and CEO of Agenus. “iNKT cells can be produced at scale and to this point individuals During this trial have tolerated the treatment method nicely.†Dose escalation is expected for being finished in the 1st fifty percent of this year for an initiation right into a Section two trial with info readouts expected during the fourth quarter of the calendar year. About AgenTus Therapeutics, Inc. AgenTus Therapeutics is often a biopharmaceutical enterprise focused on creating allogeneic iNKT cell therapies to take care of cancer and various everyday living-threatening illnesses. AgenTus also aims to progress adoptive cell therapy formats which might help off-the-shelf dwelling prescription drugs. AgenTus has places in Lexington, MA and Cambridge, United kingdom. For more info, make sure you pay a visit to . About AgenusAgenus is actually a medical-phase immuno-oncology enterprise centered on the discovery and improvement of therapies that have interaction the body's immune system to struggle cancer.